The Arizona Cardinals are coming off their first loss of the season last Thursday and head into Sunday’s game versus the San Francisco 49ers with a ton of injuries to key offensive players including quarterback Kyler Murray, who is questionable.
The 49ers are coming off a 33-22 win at Chicago last week but are still just 1-4 SU in their last five and lost 17-10 as six-point road dogs versus the Cardinals in Week 5. Arizona comes into this NFC battle tied for the best record in the division and a slight 1-point favorite, with the total sitting at 46.
If you’re betting this game on Sunday, November 7, then make sure you read our free NFL betting picks and predictions for the Cardinals vs. 49ers first.